How exactly do you expect to kill or remove mold without it ? You can’t even clean your hvac systems coils without moisture of some type ,if you use a steam cleaner you can literally clean the whole system minus the electronics . You should do more research and possibly talk to people who do the work before posting , but don’t listen to me i only have a class A contractor license ,epa license , install /repair hvacs , rent and flip houses for a living .
Ok what you said is true but in most cases ducts are in a duct flex format, and knowing that the dust in people's flex duct is just surface dust, any real debris that are in the duct itself will result in very little to no air flow which will keep your unit from performing properly, but if it is true allergy reasons then replacing your duct system is better for overall better air quality, plus if you do pay attention to the warranty on flexible duct is that it only has a 10 year warranty and typically only lasts for 20 years so do your research before having a duct cleaning, and to add one more thing if your duct work is completely metal and you can't see visible insulation then your duct on the inside has insulation inside of it, if you replace that with duct work that is clean metal on the inside and wrapped with insulation on the outside then it will further reduce the air bourne fiberglass and dust.
And if you have flex duct and/or fiberglass ductboard in your home- the last thing you want is a big brush or anything abrasive running through it. Even high-pressure air can erode ductboard so I wouldn’t clean it with anything. If it becomes contaminated, get rid of it and install real ductwork. If your ductwork is accessible in the basement – the best thing to do is take it down and manually clean it if it’s full of junk. It’s not going to cost a nickel more to do that than to pay $500-1000 for a ‘duct cleaning machine” AKA big blower and vacuum – to do the job.

Stick with a maximum of 16 SEER units in most cases.  Like I said above, contractors push higher SEER units because they make more money, but these units can be expensive at this stage of development, and can drive up your HVAC installation cost.  21 SEER units run about twice the price of a 14 SEER unit, so unless you live in a desert and plan on being there for 30 more years... Likewise, a 16 SEER unit typically costs only about $600-$1,000 more than a 14 SEER, and will usually pay for itself over the lifetime of the unit.
I just bought a home, and the sellers clearly never had the air ducts cleaned. This is, unfortunately, typical of their neglect of the home, so I am not surprised. I was cleaning around the wooden floor registers, and I took the registers off. I found nests of some sort...all kinds of really gross stuff!! I am calling now to schedule duct cleaning for my new home. Anyway, it is very easy to check to see if you really need duct cleaning. Remove the floor registers and use a flashlight if necessary to see if there is dust or debris in the ducting. If these look bad, I'd definitely have the system cleaned. I would also do it after a construction project, after installing a new furnace, etc. I have found that once I had my previous system cleaned, it seemed to remain spotless for 3 years. So it seems that if you just change your filters on time (I have an iPhone alert set for every 3 months), the system will stay clean for years. Hope this helps!

 The A/C System Cleaning and restoration industry has become a very lucrative bait and switch industry that many Carpet cleaning companies, Maid services, as well as plumbing or handyman service companies are adding on to there services. These add-ons are not fully certified, trained or even have any experience in the HVAC industry. These companies are the reason prices and quality of work are all over the place. If you are looking to make a smart decision for your home a professional Duct Cleaning service will protect you for 5-7 years. This info comes from NADCA (National Air Duct Cleaning Association) which is the closest thing to a license we have for duct cleaning. They have a great site that explains this process and pricing much more in depth and factual than what has been written here. This organization is working very hard to get these bad companies exposed and out of this industry. So in saying that do your research! Green Duct Decontamination is a certified company with certified technicians that take this work very seriously. We can not have these low rated unprofessional companies paste a bad name for an entire industry. Stay away from anything under 250$ for a full duct clean this is not feasible, go look at and you will understand why and what these companies are doing to rob you of your dollar.
The short answer is yes, duct cleaning, done right by a reputable company will help with the smell. It is likely though the smell is coming from another source, ie the crawl space. It could also be that another rodent is dead in the duct work. A visual inspection would be in order to check for any breach in the duct system. A duct pressure test would be able to tell you how much air is leaking from the system over all. A hole large enough for an animal to enter would loses a great deal of air, over 300 CFM. It would be worth looking into having this test done and it should cost around $200. Cleaning the air handler and evaporator coil will greatly improve the performance of the air conditioner. Dirt and dust on the evaporator acts as insulation and reduces the amount of cooling done be the coil. Any quality duct cleaning should include cleaning the air handler and coil, and the tech should allow you to watch him perform the work as it is done.
Concrete Blocks -- Concrete blocks are used in foundations and are often found in full basements. Insulating the spaces in the blocks is not the way to insulate them as the heat energy will travel along the concrete itself. The best way to insulate with concrete blocks is to use insulated concrete blocks, which have polystyrene incorporated into them.

Our HVAC Ductwork Installation Cost Guide is the most comprehensive guide of its type. It fully explains the purpose of ductwork and all your options. Pricing is included for all duct types and plenums/drops too. Material and installation costs are listed. Ductwork cost varies greatly by the size and type of duct plus the complexity of the installation, but you can expect to pay $10.20 to $17.25 per linear foot installed.
I am a service technician [since '92].....and as to double filtering.....I have never recommended it. would be noticeably helpful if the fiberglass filters are the main ones used [which I also never long as system can deliver appropriate air flow with a pleated cotton filter...and any decent service tech can check the air flow for proper cfm]. Any particles small enough to pass through a pleated cotton filter are going to pass through a second filter as well....unless the second filters are so tight that the system is starving for air flow. Has anybody ever accidentally put two filters in their automatic drip coffee maker? What if cars used two fuel filters or air filters? I have told some homeowners to try using second filters at each register [the black thin filter material cut-to-fit....same type used in many window air conditioners].....but I only suggest this when I know they will still get at least 400 cfm per ton of air flow [350 absolute minimum] some homeowners know others who say it has helped and it gives them a peace of mind knowing they are doing something to help contribute to a solution, so it HAS to help [even though I think it falls in the "one-born-every-minute" category.....similar to duct cleaning].

You should be aware that although a substance may look like mold, a positive determination of whether it is mold or not can be made only by an expert and may require laboratory analysis for final confirmation. For about $50, some microbiology laboratories can tell you whether a sample sent to them on a clear strip of sticky household tape is mold or simply a substance that resembles it.