The cooling coils the air comes into contact with appear to need UV-C lights on them in humid climates. That's the biggest thing. If the ducts have never been cleaned, then getting that done goes without saying. But those coils need to be cleaned, disinfected, and then UV-C light(s) installed to prevent mold & bacteria build-up in the future on them. That appears to be chiefly responsible for the dirty laundry and/or sour milk smell coming from forced-air AC systems in humid regions.
They are also often harder to install. A proper location on the roof must be selected that can support the weight of the unit. Then a platform must be built and a drain pipe for the unit must be run along the roof to avoid problems with mold and corrosion. A crane must be used to lift the unit onto the roof while a team guides it into place and hooks it up.

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Because an air conditioner moves heat between the indoor coil and the outdoor coil, both must be kept clean. This means that, in addition to replacing the air filter at the evaporator coil, it is also necessary to regularly clean the condenser coil. Failure to keep the condenser clean will eventually result in harm to the compressor, because the condenser coil is responsible for discharging both the indoor heat (as picked up by the evaporator) and the heat generated by the electric motor driving the compressor.
Ok what you said is true but in most cases ducts are in a duct flex format, and knowing that the dust in people's flex duct is just surface dust, any real debris that are in the duct itself will result in very little to no air flow which will keep your unit from performing properly, but if it is true allergy reasons then replacing your duct system is better for overall better air quality, plus if you do pay attention to the warranty on flexible duct is that it only has a 10 year warranty and typically only lasts for 20 years so do your research before having a duct cleaning, and to add one more thing if your duct work is completely metal and you can't see visible insulation then your duct on the inside has insulation inside of it, if you replace that with duct work that is clean metal on the inside and wrapped with insulation on the outside then it will further reduce the air bourne fiberglass and dust.
Multiple inventions within this time frame preceded the beginnings of first comfort air conditioning system, which was designed in 1902 by Alfred Wolff (Cooper, 2003) for the New York Stock Exchange, while Willis Carrier equipped the Sacketts-Wilhems Printing Company with the process AC unit the same year. Coyne College was the first school to offer HVAC training in 1899.[12]
In the middle of summer—even more so in North America—AC repairs are undoubtedly the last thing you want to have to think about. But that won’t keep them from taking place. Fortunately, Service Experts Heating & Air Conditioning is dedicated to completing expert quality AC repair, maintenance and installation throughout the North America area. We certainly don’t want you to be stuck in an uncomfortable home during the hottest days of summer. 

I am a service technician [since '92].....and as to double filtering.....I have never recommended it. Granted.....it would be noticeably helpful if the fiberglass filters are the main ones used [which I also never recommend.....as long as system can deliver appropriate air flow with a pleated cotton filter...and any decent service tech can check the air flow for proper cfm]. Any particles small enough to pass through a pleated cotton filter are going to pass through a second filter as well....unless the second filters are so tight that the system is starving for air flow. Has anybody ever accidentally put two filters in their automatic drip coffee maker? What if cars used two fuel filters or air filters? I have told some homeowners to try using second filters at each register [the black thin filter material cut-to-fit....same type used in many window air conditioners].....but I only suggest this when I know they will still get at least 400 cfm per ton of air flow [350 absolute minimum]......as some homeowners know others who say it has helped and it gives them a peace of mind knowing they are doing something to help contribute to a solution, so it HAS to help [even though I think it falls in the "one-born-every-minute" category.....similar to duct cleaning].
Whether or not central air adds value to your home depends on your location. You probably won't recoup the entire cost for the installation, as it is an expensive project that isn't as flashy as something like a new deck. But this invisible upgrade can help you sell your home if you live in a hot climate. And many buyers are willing to pay a bit more for a working AC.

Having the most energy-efficient system ever built won't matter much if it's not maintained. Lack of maintenance is the number one killer of HVAC systems. Before each cooling season, it's recommended that your system get a professional tune-up. However, there are things you can do in the meantime to make sure your system runs efficiently throughout the year.
From Day 1, Alberto walked us through the process, and present us with a variety of options based our budget for the project. His customer service is the best as he did not oversell any services and did not nudge us towards buying a unit that would stretch our budget. On installation day, HVAC Services sent out a crew of 6-7 guys, all of whom were very polite and kept their work areas clean, and installed the whole system the same day.
A thorough visual inspection is the best way to verify the cleanliness of your heating and cooling system. Some service providers use remote photography to document conditions inside ducts. All portions of the system should be visibly clean; you should not be able to detect any debris with the naked eye. Show the Post-Cleaning Consumer Checklist to the service provider before the work begins. After completing the job, ask the service provider to show you each component of your system to verify that the job was performed satisfactorily.
All of the products discussed above are registered solely for the purpose of sanitizing the smooth surfaces of unlined (bare) sheet metal ducts. No products are currently registered as biocides for use on fiber glass duct board or fiber glass lined ducts, so it is important to determine if sections of your system contain these materials before permitting the application of any biocide.

The next step was cleaning the cold air returns. He found a good spot to drill an 8” hole for his vacuum hose. The procedure matched the other air ducts except that when he finished at the two cold return registers he drilled several holes in the cold ducts in the basement and blasted air into them. Because of our houses age and the upgraded return system, I noticed that the main sheet metal return duct had no top but was just butted up against the ceiling in the basement. When he blasted air in, dust and crap shot out the edges along the ceiling. Once he finished that he removed the filter and “swept” out anything at the bottom of the return with his hand into the 8” hose.
The most recognized standards for HVAC design are based on ASHRAE data. The most general of four volumes of the ASHRAE Handbook is Fundamentals; it includes heating and cooling calculations. Each volume of the ASHRAE Handbook is updated every four years. The design professional must consult ASHRAE data for the standards of design and care as the typical building codes provide little to no information on HVAC design practices; codes such as the UMC and IMC do include much detail on installation requirements, however. Other useful reference materials include items from SMACNA, ACGIH, and technical trade journals.
Important Tip: Don’t just pay attention to the high-end of the price range! – which is what I know you are all looking at, but also look at the low range. If a contractor is cheaper than this, ask “why?” Usually it is because they don’t have liability insurance, workman’s compensation insurance, are unlicensed, all of the above, or worst yet, they don’t use HVAC technicians. You are spending a lot of money.  Make sure that they are licensed (In California, check here at CSLB License Checker) and insured.
Some of the research I have done suggests to have your ducts cleaned when you first purchase a new home to remove drywall dust. Maintain your system well and you shouldn't have to do it again until you want to sell. Those are the two times cleaning was suggested. So for peace of mind maybe it is a good idea to do it even if you buy a used home and then maybe every 5-10 years.
Manufacturers of products marketed to coat and encapsulate duct surfaces claim that these sealants prevent dust and dirt particles inside air ducts from being released into the air. As with biocides, a sealant is often applied by spraying it into the operating duct system. Laboratory tests indicate that materials introduced in this manner tend not to completely coat the duct surface. Application of sealants may also affect the acoustical (noise) and fire retarding characteristics of fiber glass lined or constructed ducts and may invalidate the manufacturer's warranty.
On the other hand, if family members are experiencing unusual or unexplained symptoms or illnesses that you think might be related to your home environment, you should discuss the situation with your doctor. EPA has published the following publications for guidance on identifying possible indoor air quality problems and ways to prevent or fix them.
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