The most recognized standards for HVAC design are based on ASHRAE data. The most general of four volumes of the ASHRAE Handbook is Fundamentals; it includes heating and cooling calculations. Each volume of the ASHRAE Handbook is updated every four years. The design professional must consult ASHRAE data for the standards of design and care as the typical building codes provide little to no information on HVAC design practices; codes such as the UMC and IMC do include much detail on installation requirements, however. Other useful reference materials include items from SMACNA, ACGIH, and technical trade journals.
I can't believe the number of people saying a good properly installed central heating system never needs to be cleaned. Maybe they live in hermetically sealed cells? One look into a cold air return and you can see that it definitely needs periodic cleaning. The air in the house "always" has some dust in it and that's where it ends up. We just had ours cleaned and I saw what came out of it, disgusting. But always ask if they use the "air whip" to sweep/beat the inside of the metal duct. If not, don't bother. These folks used a little whip on the end of a pressure hose and swept the entire length of all the ducts. I have lighted bore scope that allowed me to see into the duct after he was done and it was spic and span. But do change your filters often, 2 or 3 times a year.
The three major functions of heating, ventilation, and air conditioning are interrelated, especially with the need to provide thermal comfort and acceptable indoor air quality within reasonable installation, operation, and maintenance costs. HVAC systems can be used in both domestic and commercial environments. HVAC systems can provide ventilation, and maintain pressure relationships between spaces. The means of air delivery and removal from spaces is known as room air distribution.
A little simple math can help determine the size system you need. A rule of thumb is 20 BTUs per square foot. So, a 500 square foot room would need 10,000 BTUs to cool or warm it efficiently. This assumes that you live in a temperate region and have adequate insulation with no energy loss. In the real world, all units have some degree of energy loss. This is reflected in an HVAC system's SEER rating for cooling and AFUE rating for heating.
You should be aware that although a substance may look like mold, a positive determination of whether it is mold or not can be made only by an expert and may require laboratory analysis for final confirmation. For about $50, some microbiology laboratories can tell you whether a sample sent to them on a clear strip of sticky household tape is mold or simply a substance that resembles it.