Yes everyone should get all their ductwork cleaned, because it does help, incame down with major allergies and had serval operations on my sinues because of this problem of air quality and dust, plus i almost died from one of the operations, i was suffering so much. Yes you can seal your duct system by buyind duct seal t instead of tape to tape all the corners of the vent system, tape wears out and gets brittle, the sealant you can buy at home depot, and you just brush it all over the connections of your ductwork, it comes in a container and it is like a thick paste and dries making a good seal for your ductwork.
My father started in the business of home comfort back in 1968, an I around 1986. We still don't have a duct cleaning machine. I am sure there are always applications for all tools in this industry. However I missed where anyone talked about where dust even comes from..........We do not have these little dust machines sitting in a corner puffing out little clouds of dust....soooo where does it come from?
The short answer is yes, duct cleaning, done right by a reputable company will help with the smell. It is likely though the smell is coming from another source, ie the crawl space. It could also be that another rodent is dead in the duct work. A visual inspection would be in order to check for any breach in the duct system. A duct pressure test would be able to tell you how much air is leaking from the system over all. A hole large enough for an animal to enter would loses a great deal of air, over 300 CFM. It would be worth looking into having this test done and it should cost around $200. Cleaning the air handler and evaporator coil will greatly improve the performance of the air conditioner. Dirt and dust on the evaporator acts as insulation and reduces the amount of cooling done be the coil. Any quality duct cleaning should include cleaning the air handler and coil, and the tech should allow you to watch him perform the work as it is done.
Though this installation is not always complicated, it's best to work with an air conditioning contractor to ensure it's done correctly. Permits are usually required for this type of work and can be obtained by a state-licensed contractor. You should not attempt to install central air conditioning on your own since you need a license to handle the refrigerant chemicals (Freon) involved.

We are all getting migraines several times a month. I have asthma but not ever as bad as it has been and my 2 year olds dr just informed me she potentially has asthma too. We all get sinus infections regularly and eczema and contact dermatitis. None of us have been this way until recently in our apartment. A roof leak with mold was repaired recently mold was sealed off not removed. We also had lead paint removed from a few window trims this year. I wasn’t here to see if they covered the vents. We had mice too. I vacuum everyday we have hardwood floors no one wears shoes past the font door and I’m getting over a cup full of dirt every time I vacuum. Dust on everything daily. White dust. It’s a 4 room apartment with 1 intake. They are filthy from what I can see when I change the filters. The filters are black after a few months. I feel bad to ask the homeowner to get the system cleaned, can’t afford to move (we live in the city & it’s expensive). I am going to try the shop vac to remove what I can. Any experienced hvac people please give your opinion. Should I just get it done and pay for it myself? We have lived here for 13 years. It’s never been cleaned since ive been here. Is it something I can do with a shop vac? Can i use a wet rag to get the powder dust on the inside of the vents off. One vent has what looks like chunks of dry wall or thick paint sitting in the vent and none of the vents screw into the wall, the screws just fall out. No one ever reinforced the area so the wall just basically crumbles. Kind of useless to spend the money on filters since the air and dust just blows out around the sides of the vents and one of the vents just falls right out of the wall when the heat is turned on. I don’t know why the owner doesn’t fix it. He’s been here to replace filters and saw the condition.
Greetings from Mama Duck from Ductz of Greater Atlanta. These are some awesome comments and a few are from high quality duct cleaners that I personally know. After 19 years in this industry I agree that a government agency is not always up to date with their knowledge but won't admit it. If they were out in the field with our technicians every day they would upgrade their info. I get calls all the time where customers have been taken advantage of by "go and blow" companies. The customers don't know what they don't know but many are too lazy to do the research and are just looking for cheap. The industry has gotten a bad rap due to these con artists but the customer has to take some responsibility. I ask them why they would want to do business with a company who lies to them in print? Are they stupid or just cheap? Thankfully there are those of us in the industry who are working diligently to raise the bar on quality, protect the consumer and perform high quality work. At Ductz all our technicians are NADCA certified, trained by the best in the industry and know how to clean the entire system.

An energy recovery ventilator: This component helps improve the air inside your home by swapping it out with fresh air from the outside. During the winter months when houses are closed up to keep out the cold, the air inside becomes a handy way for colds and flu to infect an entire family. By circulating outside air inside, the health of your family will have a better chance.
My Carrier furnace occasionally (one-two times a day) does not start. It shows error code 15 ("BLOWER MOTOR LOCKOUT -This status code indicates the blower failed to reach 250 RPM or the blower failed to communicate to the variable speed furnace control within 30 seconds after being turned ON in two successive heating cycles."). However, when I turn off and on the furnace power switch it starts and runs fine for a while. Sometimes it runs fine all day, but does not start only once in the evening or in the night. It is 13 years old I was thinking to replace whole thing if repair cost is too high. But I am not ready to pay $10,000. 
PickHVAC Tips: Oil burns dirty, so it is important to have your plenum and ducts checked to see if they should be cleaned when replacing an oil furnace. If you don’t clean the plenum and ducts when replacing the furnace, the new furnace might not run as efficiently and comfortably as possible due to restricted airflow. This can also reduce the oily smell sometimes associated with oil furnaces.
Indoor Fan Motor -- Indoor fans circulate the air from your house and through the system. Age and dust buildup are the two biggest contributing factors to their failure. When they are starting to fail they will often make noise. Failure of the fan will result in no heating or cooling, and if it is not repaired soon, it can cause other components to fail.
All these pro duct cleaners answer with "it's common sense, everything operates better when cleaner" etc. But your explanation is correct. Especially so with flex tube ducting where dust gets "stuck" between the lowest valleys (between wire coil supports) where air flow is drastically reduced -- which is more than 50 pct of the entire interior surface area of the flex ducting. That sounds like a bad thing but also has a good effect of trapping dust from escaping.

In addition, the service provider may propose applying chemical biocides, designed to kill microbiological contaminants, to the inside of the duct work and to other system components. Some service providers may also suggest applying chemical treatments (sealants or other encapsulants) to encapsulate or cover the inside surfaces of the air ducts and equipment housings because they believe it will control mold growth or prevent the release of dirt particles or fibers from ducts. These practices have yet to be fully researched and you should be fully informed before deciding to permit the use of biocides or chemical treatments in your air ducts. They should only be applied, if at all, after the system has been properly cleaned of all visible dust or debris.
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