The cooling coils the air comes into contact with appear to need UV-C lights on them in humid climates. That's the biggest thing. If the ducts have never been cleaned, then getting that done goes without saying. But those coils need to be cleaned, disinfected, and then UV-C light(s) installed to prevent mold & bacteria build-up in the future on them. That appears to be chiefly responsible for the dirty laundry and/or sour milk smell coming from forced-air AC systems in humid regions.

If your non metal ductwork is that dirty you should just have it replaced AND sealed. Also most duct systems are not very well designed. Look for proper sizing and do not go cheap with one or two intakes (return grills) You need them through-out the house. Here in Austin the duct cleaners are carpet cleaners and chimney swifts. (this is who the duct cleaning equipment mfgs call on when the hvac people do not get on board. They DO clean other types of ductwork and we (the hvac guys) have to fix them. I am not aware of any of these non hvac guys cleaning and servicing the actual equipment. Here in Texas it is against the law for them to do so. Treat the entire house as a system, not just the ductwork and /or hvac equipment. Home performance really does work to increase comfort and air quality while reducing operating costs.

While you consider having your air ducts cleaned, it is a good idea to take a look at your dryer vent. If your dryer vent is clogged, you could be losing energy efficiency. Worse yet, you could be increasing the risk of a house fire. Having your dryer vent professionally cared for costs about $130 on average, and could save you a bit of money and a lot of headaches in the future. For more information on the benefits and cost of having your dryer vent cleaned, take a look at our comprehensive cost guide.
My 48 yr old house (mine for the last 4 yrs) has considerable dust in the return plenum (fiber duct). I’m remodeling and recently re-sealed the return plenum AND the site-fabbed transition built when the new unit was installed, 2013. The return was leaky no doubt drawing musty, dusty air from the crawl space due to the Red-Neck fab & seal job! Pitiful craftsmanship! It took me 7 hours to fix the new transition piece. Anyway, the dust in the house is the same “color” as whats in the return duct and I’m getting way too much & too often in the house. I’ve also cleaned my coils, which were not that dirty.
I need a complete system replacement , before I was trying to get an evaporator coil replaced , of course the price is between $2200 an $2800 , then get told it probably will over tax my ac unit within months , so now and like everyone else what do you buy 14 ,15 16 17 seer units ,price and how do we know its reasonable  why can't there be '" a estimated price ,in the ball park, a range of prices ,so we can at least go from their .....  Now it's from 7500 to 15000. Frustrating  from the start so everybody good LUCK.   Draw a # from the hat    Unregulated  and who do you BELIEVE, just like on NCIS go with your gut feelin   
Tip – Be careful with change-outs. Ductwork deteriorates and sometimes has to be replaced.  It is only if the ductwork is in fantastic condition that you should get a change-out without ductwork (Remember – the ductwork has already been there for 15-20 years, and now it will be there another 15-20…it has to be in good shape). However, many HVAC installation companies like to push change-outs because the ductwork is the most time consuming part of the job, and a change-out is quick, easy money. Realize that it’s only about 15-20% of the jobs that qualify for a change-out, so be careful.
I had my ducts somewhat cleaned December 22, 2014. The hose of the machine the technitian used did not fit in some of my vents, therefore, he did not clean them. But I still paid $428.00 for the service. I will be calling the company on Monday, and kindly ask them to come back and clean the ducts they did not as they did not fullfill their part of the service.
Typically speaking, the lower SEER, more basic models are also more reliable.  Reliability is big with us, so we steer clear of features with reliability issues, and it’s as simple as that. When you factor in the price of repairs and the extra expense of the 21-SEER, you may actually lose money! 16 SEER is the sweet-spot, and it is key to reducing your HVAC installation cost.
The bottom line is: no one knows. There are examples of ducts that have become badly contaminated with a variety of materials that may pose risks to your health. The duct system can serve as a means to distribute these contaminants throughout a home. In these cases, duct cleaning may make sense. However, a light amount of household dust in your air ducts is normal. Duct cleaning is not considered to be a necessary part of yearly maintenance of your heating and cooling system, which consists of regular cleaning of drain pans and heating and cooling coils, regular filter changes and yearly inspections of heating equipment. Research continues in an effort to evaluate the potential benefits of air duct cleaning.
NADCA and EPA both have good points. Although, organizations are made to make money. Common sense and looking at NADCA and EPA pre-checklist. If you don't see it in the check list, you don't have to do it! But, if you do, look up Diamond certified co.s and the BBB. Beware of bait and switch scams, $60 vents and the like coupons which claim to help all for the measley sum of $79.00 bucks.
HELP is am drowing in LENT . It has been noticed in the master bedroom there is lent all over the furniture and the floors. I have dark brown/black furniture and same for the wooden floors. There are wods of lent every day. My furniture covered in lent. The rest of the house is fine just the tipical dust. I am sure my lungs are also full of lent. I looks like if my dryer vent was in my bedroom. Please help
Some systems include an "economizer mode", which is sometimes called a "free-cooling mode". When economizing, the control system will open (fully or partially) the outside air damper and close (fully or partially) the return air damper. This will cause fresh, outside air to be supplied to the system. When the outside air is cooler than the demanded cool air, this will allow the demand to be met without using the mechanical supply of cooling (typically chilled water or a direct expansion "DX" unit), thus saving energy. The control system can compare the temperature of the outside air vs. return air, or it can compare the enthalpy of the air, as is frequently done in climates where humidity is more of an issue. In both cases, the outside air must be less energetic than the return air for the system to enter the economizer mode.
SEER is useful for comparing one model to another much in the same way that a car's calculate MPG is useful. It's not an accurate prediction of exactly how efficient the system is, but it can tell you which one is more efficient. Also, since SEER is based on a "cooling season", what region you live in will determine how long or short your cooling season is.
If there is stuff in the ducts, the fact that it’s laying there and not being blown into the rooms is proof positive that it is hurting no-one. The 5-6 exceptions you cite in this article I’ll buy, but only with the caveat that at least some of those could have been avoided by proper protection (during remodeling for example) – and if asbestos/lead/whatever winds up in your ducts- the remodeling contractor should be the one paying to remove it.
On the other hand, if a service provider fails to follow proper duct cleaning procedures, duct cleaning can cause indoor air problems. For example, an inadequate vacuum collection system can release more dust, dirt and other contaminants than if you had left the ducts alone. A careless or inadequately trained service provider can damage your ducts or heating and cooling system, possibly increasing your heating and air conditioning costs or forcing you to undertake difficult and costly repairs or replacements.
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