Manufacturers of products marketed to coat and encapsulate duct surfaces claim that these sealants prevent dust and dirt particles inside air ducts from being released into the air. As with biocides, a sealant is often applied by spraying it into the operating duct system. Laboratory tests indicate that materials introduced in this manner tend not to completely coat the duct surface. Application of sealants may also affect the acoustical (noise) and fire retarding characteristics of fiber glass lined or constructed ducts and may invalidate the manufacturer's warranty.

I know it has to have a new concentric venting system installed, I believe it needs new plenums ( mine are rusty but both of these require extra work , so someHVAC persons are saying I do not need either!! RED FLAG THERE. Also, it will need a new drain using PVCP ?? Piping run maybe two, depending on where my evep coil drain is conected (here in TN they use to run them in with the septic lines, now they cannot be run through that way), Lastly I am not where or what these things do beides hold water but I was told It needs a filter rack and new filter base safety pan. THATSSS it that is all I know about this stuff aside from the fact that nothing up there is to code thus far LOL. !!
My point is that the brand of equipment you choose is going to affect your HVAC installation cost greatly. People often call us for an air conditioning installation job and say, “I would like to install Carrier equipment.” Now, if you are a future client of ours, I’ll have to warn you – I can be a bit of a smart-ass. Why can’t work be fun? Besides…I was in the Navy for 11 years, what do you expect. 
The fact is if they are dirty why not clean them. As for the Dr’s comment about if it is not disrupted it is fine. As a pet owner sometimes un disrupted pet hair will sit in the corner of a room or under a counter un disrupted but I still clean it when I notice it. Just because you cant see it doesn’t mean you should leave it there to collect more and more. The people that don’t want there air ducts clean either simply cant afford it but would like it done. OR! the crowd that are to cheap.. You should Clean all portions of your house.
What you might not know is that the brand you choose is one of the most important factors in determining a fair HVAC installation cost. So, before delving in-depth, let’s take a quick look at the average prices of a new air conditioner and matching coil by brand…keep in mind, these are the average prices (by brand) that contractors pay for your AC equipment, and it is meant to give you a rough guideline until you are closer to buying:
Multiple inventions within this time frame preceded the beginnings of first comfort air conditioning system, which was designed in 1902 by Alfred Wolff (Cooper, 2003) for the New York Stock Exchange, while Willis Carrier equipped the Sacketts-Wilhems Printing Company with the process AC unit the same year. Coyne College was the first school to offer HVAC training in 1899.[12]
The performance of vapor compression refrigeration cycles[26] is limited by thermodynamics. These air conditioning and heat pump devices move heat rather than convert it from one form to another, so thermal efficiencies do not appropriately describe the performance of these devices. The Coefficient-of-Performance (COP) measures performance, but this dimensionless measure has not been adopted. Instead, the Energy Efficiency Ratio (EER) has traditionally been used to characterize the performance of many HVAC systems. EER is the Energy Efficiency Ratio based on a 35 °C (95 °F) outdoor temperature. To more accurately describe the performance of air conditioning equipment over a typical cooling season a modified version of the EER, the Seasonal Energy Efficiency Ratio (SEER), or in Europe the ESEER, is used. SEER ratings are based on seasonal temperature averages instead of a constant 35 °C (95 °F) outdoor temperature. The current industry minimum SEER rating is 14 SEER.[27][dead link]
Be careful of dishonest HVAC contractors. There’s no magical formula to see if an HVAC contractor is scamming you, unfortunately, but remember that they typically do this in one of two ways: first, they are charging grossly low prices (far below everyone else), or second, they aren’t including what everyone else is. In the first situation, they will charge you change fees, other hidden fees, or they stole the equipment and are passing themselves off as legitimate contractors (very common in California these days). In the second situation, they are charging you a very fair price, but aren’t including what the other contractors are (i.e. charging $10,500 for the installation which is fair, but not including the ductwork which is a scam unless there is some other, complex stuff going on there).

Had our ducts cleaned late April, 2016. Sodium Chlorite was sprayed into ducts after cleaning. Ever since, we have been bothered with eye and nasal passage irritation because of a “chemical” and “musty” odor. This odor is present whether or not a/c is on.) We are told the sodium chlorite (“EnviroCon, manufactured by Bio-Cide International) is used in hospital and nursing home settings and is not hazardous to health. The air duct company’s suggestion is that they come out and spray even more sodium chlorite…we absolutely don’t want this done! Have had various other recommendations about what we need to have done to remedy our problem. We will be unable to stay in our home if a resolution cannot be found. We’d be willing to replace the ductwork if necessary. (One professional suggested that the cleaning may have “knocked something loose” inside the ductwork and that is the source of the irritant.) This home was built in 1920…no idea when the present ductwork was installed. Any suggestions would be appreciated.

Ground source, or geothermal, heat pumps are similar to ordinary heat pumps, but instead of transferring heat to or from outside air, they rely on the stable, even temperature of the earth to provide heating and air conditioning. Many regions experience seasonal temperature extremes, which would require large-capacity heating and cooling equipment to heat or cool buildings. For example, a conventional heat pump system used to heat a building in Montana's −70 °F (−57 °C) low temperature or cool a building in the highest temperature ever recorded in the US—134 °F (57 °C) in Death Valley, California, in 1913 would require a large amount of energy due to the extreme difference between inside and outside air temperatures. A few feet below the earth's surface, however, the ground remains at a relatively constant temperature. Utilizing this large source of relatively moderate temperature earth, a heating or cooling system's capacity can often be significantly reduced. Although ground temperatures vary according to latitude, at 6 feet (1.8 m) underground, temperatures generally only range from 45 to 75 °F (7 to 24 °C).

Outdoor Fan Motor -- The outdoor fan, also called the condenser fan, is exposed to external conditions. As such it is most prone to dust and debris and the extreme weather. In desert climates, the outdoor fan motor is subject to heat not only from normal operation but from the outside temperature as well. As it starts to fail, the fan may work fine in the cooler morning hours but stop by afternoon. This can shut down the entire system for hours. When they stop running completely, your air conditioner will no longer work. Running a faulty fan will lead to compressor failure, which is a very costly repair.
Some of the research I have done suggests to have your ducts cleaned when you first purchase a new home to remove drywall dust. Maintain your system well and you shouldn't have to do it again until you want to sell. Those are the two times cleaning was suggested. So for peace of mind maybe it is a good idea to do it even if you buy a used home and then maybe every 5-10 years.
I can't believe the number of people saying a good properly installed central heating system never needs to be cleaned. Maybe they live in hermetically sealed cells? One look into a cold air return and you can see that it definitely needs periodic cleaning. The air in the house "always" has some dust in it and that's where it ends up. We just had ours cleaned and I saw what came out of it, disgusting. But always ask if they use the "air whip" to sweep/beat the inside of the metal duct. If not, don't bother. These folks used a little whip on the end of a pressure hose and swept the entire length of all the ducts. I have lighted bore scope that allowed me to see into the duct after he was done and it was spic and span. But do change your filters often, 2 or 3 times a year.

Indoor Fan Motor -- Indoor fans circulate the air from your house and through the system. Age and dust buildup are the two biggest contributing factors to their failure. When they are starting to fail they will often make noise. Failure of the fan will result in no heating or cooling, and if it is not repaired soon, it can cause other components to fail.

I’m having my duct work cleaned this Saturday. Have a coupon for $49 through Amazon. Job normally $249. Had my basement remodeled about 18 months ago. The contractors were very thorough at blocking the vents, as far as I can tell. The offer is for HVAC and dryer vent cleaning. My house is 11 years old. I figured, $49 is not much. I appreciate your tips on not getting talked into any additional service, not to use solvents to clean, the certification information and before and after pictures. Very useful and I’ll be sure that all I spend is the $49 for the voucher.
The amount of debris or mold present in your system could certainly ratchet up the overall price. The cost of mildew removal is around $0.07-0.08 per square foot, on top of your initial cost, according to Blue Book. Removing these elements involves added time, special equipment and even special chemicals. In fact, you may be referred to a specialist if mildew and mold is too severe.

Some research suggests that cleaning heating and cooling system components (e.g., cooling coils, fans and heat exchangers) may improve the efficiency of your system, resulting in a longer operating life, as well as some energy and maintenance cost savings. However, little evidence exists that cleaning only the ducts will improve the efficiency of the system.