Some systems include an "economizer mode", which is sometimes called a "free-cooling mode". When economizing, the control system will open (fully or partially) the outside air damper and close (fully or partially) the return air damper. This will cause fresh, outside air to be supplied to the system. When the outside air is cooler than the demanded cool air, this will allow the demand to be met without using the mechanical supply of cooling (typically chilled water or a direct expansion "DX" unit), thus saving energy. The control system can compare the temperature of the outside air vs. return air, or it can compare the enthalpy of the air, as is frequently done in climates where humidity is more of an issue. In both cases, the outside air must be less energetic than the return air for the system to enter the economizer mode.
After one company just took a cursory glance at our A/C and found nothing wrong, I called HVAC. I called them mostly based on Michael W's post on 8/10/14 where he told us the owner, Alberto, took his feedback and took it SERIOUSLY. That speaks VOLUMES to anyone who has been around long enough to know the characteristics of the serious players are and those who are the wannabes.
So, naturally I respond with, “you don’t tell your doctor which medication to prescribe you, do you?” The point is, on the residential level, who you get to install your HVAC unit is far more important than which unit you choose.  Keep your options open and let your HVAC contractor make a few recommendations – that’s why you spent time finding a reputable contractor!
While you consider having your air ducts cleaned, it is a good idea to take a look at your dryer vent. If your dryer vent is clogged, you could be losing energy efficiency. Worse yet, you could be increasing the risk of a house fire. Having your dryer vent professionally cared for costs about $130 on average, and could save you a bit of money and a lot of headaches in the future. For more information on the benefits and cost of having your dryer vent cleaned, take a look at our comprehensive cost guide.
Air duct cleaning service providers may tell you that they need to apply a chemical biocide to the inside of your ducts to kill bacteria (germs) and fungi (mold), and prevent future biological growth. Some duct cleaning service providers may propose to introduce ozone to kill biological contaminants. Ozone is a highly reactive gas that is regulated in the outside air as a lung irritant. However, there remains considerable controversy over the necessity and wisdom of introducing chemical biocides or ozone into the duct work.

My 48 yr old house (mine for the last 4 yrs) has considerable dust in the return plenum (fiber duct). I’m remodeling and recently re-sealed the return plenum AND the site-fabbed transition built when the new unit was installed, 2013. The return was leaky no doubt drawing musty, dusty air from the crawl space due to the Red-Neck fab & seal job! Pitiful craftsmanship! It took me 7 hours to fix the new transition piece. Anyway, the dust in the house is the same “color” as whats in the return duct and I’m getting way too much & too often in the house. I’ve also cleaned my coils, which were not that dirty.
Heating, ventilation, and air conditioning (HVAC) systems have been shown to act as a collection source for a variety of contaminants that have the potential to affect health, such as mold, fungi, bacteria, and very small particles of dust. The removal of such contaminants from the HVAC system and home should be considered as one component in an overall plan to improve indoor air quality.
As for the price I think my review was fair in stating what value we got for what I deemed to be a slightly higher price than others might charge.  I did not take any stars off for the price, and still am not, but I am taking another star off because of Alberto's comments, which are deceptive and not the same thing he told me in person.  Alberto, I suggest you stick with the high road in the future.
The short answer is yes, duct cleaning, done right by a reputable company will help with the smell. It is likely though the smell is coming from another source, ie the crawl space. It could also be that another rodent is dead in the duct work. A visual inspection would be in order to check for any breach in the duct system. A duct pressure test would be able to tell you how much air is leaking from the system over all. A hole large enough for an animal to enter would loses a great deal of air, over 300 CFM. It would be worth looking into having this test done and it should cost around $200. Cleaning the air handler and evaporator coil will greatly improve the performance of the air conditioner. Dirt and dust on the evaporator acts as insulation and reduces the amount of cooling done be the coil. Any quality duct cleaning should include cleaning the air handler and coil, and the tech should allow you to watch him perform the work as it is done.
1. Ducts need cleaning mostly because they were not installed properly. There should be regulatory inpection and approval of clean and proper duct works on new houses. I was extremely unpset when I looked and found significant amounts of construction dust in parts of the ducts in my new house. There is apparently no way to hold the bullder to be responsible for clean ducts.
You may consider having your air ducts cleaned simply because it seems logical that air ducts will get dirty over time and should be occasionally cleaned. Provided that the cleaning is done properly, no evidence suggests that such cleaning would be detrimental. EPA does not recommend that the air ducts be cleaned routinely, but only as needed. EPA does, however, recommend that if you have a fuel burning furnace, stove or fireplace, they be inspected for proper functioning and serviced before each heating season to protect against carbon monoxide poisoning.
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