NADCA and EPA both have good points. Although, organizations are made to make money. Common sense and looking at NADCA and EPA pre-checklist. If you don't see it in the check list, you don't have to do it! But, if you do, look up Diamond certified co.s and the BBB. Beware of bait and switch scams, $60 vents and the like coupons which claim to help all for the measley sum of $79.00 bucks.
Moisture can enter the duct system through leaks or if the system has been improperly installed or serviced. Research suggests that condensation (which occurs when a surface temperature is lower than the dew point temperature of the surrounding air) on or near cooling coils of air conditioning units is a major factor in moisture contamination of the system. The presence of condensation or high relative humidity is an important indicator of the potential for mold growth on any type of duct. Controlling moisture can often be difficult, but here are some steps you can take:

yes get a good company and pay the price, I found so much dust and dirt and wood and paint chips and bugs and even bottle caps in my ductwork. I hired a major plumbing company who cleaned ductwork and i will say they did an excellent job cleaning my vent. they did miss one point in my ductwork because i still started to see dust all over my furniture and i realized that my retunduct work that was connected with a piece of sheet metal beam which was 16" across , the contractor that built my condo used a 16" wide sheet of sheet metal to connect the vent system to my return for the air to return back into my condo. The contractor should have built a 8" x16" square duct by 6 feet long to connect my intake to my return instead of using a sheet of sheet metal 16" wide by using two 3' sections by 16 inches wide. That was a shor cut which caused a major problem fir me.
They work less jobs, thus increasing profits – think about it…if they got only half of the jobs, then they only pay half of the money required to pay employees, expenses, etc., but still have the same amount of net profit. In fact, if you do the math, they actually make more profit that their competitors do…twice as much, once you factor in their savings form only doing half of the jobs at the same amount of profit (Total Revenue – (half the normal expenses) = twice the profit). In other words, they save money by doing half of the jobs as others, for the same profit, thus increasing their overall profits.
Fresh-Aire UV is an innovation leader in the field of indoor air quality. Our award-winning UV light and carbon products fight mold, bacteria, viruses and odors in commercial and residential HVACR systems. Our products include Blue-Tube UV®, the worlds most popular germicidal UV light, the revolutionary APCO® PCO/carbon whole-house air purifier, and Mini UV the first UV light system designed specifically for mini-split AC systems.
The cost to replace a central air conditioner is about $5,000. However, this price varies depending on the size of your home and the difficulty of the project. It can cost as much as $12,500 to replace an AC unit. The labor required to remove and dispose of the old system adds to the price. The size of your home, brand of AC unit and ductwork complexity can all raise the cost as well.

Is duct cleaning worth it? There is not a yes or no answer that suits everyone. On an Air Force base, the system was not air tight and there was leakage around the filters. The system got dirty. A professional company was called out. The Duct was big enough that a technician could go inside the metal duct and clean it. There was a new Air Handler installed and things were sealed up better. in this case it was worth it.
1. Ducts need cleaning mostly because they were not installed properly. There should be regulatory inpection and approval of clean and proper duct works on new houses. I was extremely unpset when I looked and found significant amounts of construction dust in parts of the ducts in my new house. There is apparently no way to hold the bullder to be responsible for clean ducts.
Cost Factors: The size of the unit, its efficiency and it’s single-stage, two-stage or variable-capacity are the top cost factors. Features like communicating technology and improved dehumidification performance also affect the price. Learn more about communicating technology here including the pros and cons, before being agreeing to a communicating system.
Chemical biocides are regulated by EPA under Federal pesticide law. A product must be registered by EPA for a specific use before it can be legally used for that purpose. The specific use(s) must appear on the pesticide (e.g., biocide) label, along with other important information. It is a violation of federal law to use a pesticide product in any manner inconsistent with the label directions.
Duct cleaning has never been shown to actually prevent health problems. Neither do studies conclusively demonstrate that particle (e.g., dust) levels in homes increase because of dirty air ducts. This is because much of the dirt in air ducts adheres to duct surfaces and does not necessarily enter the living space. It is important to keep in mind that dirty air ducts are only one of many possible sources of particles that are present in homes. Pollutants that enter the home both from outdoors and indoor activities such as cooking, cleaning, smoking, or just moving around can cause greater exposure to contaminants than dirty air ducts. Moreover, there is no evidence that a light amount of household dust or other particulate matter in air ducts poses any risk to your health.